Cholesterol Defect Is Marked across Multiple Rodent Models of Huntington's Disease and Is Manifest in Astrocytes

Brain cholesterol, which is synthesized locally, is a major component of myelin and cell membranes and participates in neuronal functions, such as membrane trafficking, signal transduction, neurotransmitter release, and synaptogenesis. Here we show that brain cholesterol biosynthesis is reduced in m...

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Bibliografski detalji
Glavni autori: Valenza, Marta, Leoni, Valerio, Karasinska, Joanna M., Petricca, Lara, Fan, Jianjia, Carroll, Jeffrey, Pouladi, Mahmoud A., Fossale, Elisa, Nguyen, Huu Phuc, Riess, Olaf, MacDonald, Marcy, Wellington, Cheryl, DiDonato, Stefano, Hayden, Michael, Cattaneo, Elena
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2010
Teme:
Brief Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842469/
https://ncbi.nlm.nih.gov/pubmed/20702713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0917-10.2010
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