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The BACHD Rat Model of Huntington Disease Shows Signs of Fronto-Striatal Dysfunction in Two Operant Conditioning Tests of Short-Term Memory

The BACHD rat is a recently developed transgenic animal model of Huntington disease, a progressive neurodegenerative disorder characterized by extensive loss of striatal neurons. Cognitive impairments are common among patients, and characterization of similar deficits in animal models of the disease...

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Publicat a:PLoS One
Autors principals: Clemensson, Erik Karl Håkan, Clemensson, Laura Emily, Riess, Olaf, Nguyen, Huu Phuc
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207398/
https://ncbi.nlm.nih.gov/pubmed/28045968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169051
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