Mammalian Target of Rapamycin Complex 2 (mTORC2) Is a Critical Determinant of Bladder Cancer Invasion

Bladder cancer is the fourth most common cause of cancer in males in the United States. Invasive behavior is a major determinant of prognosis. In this study, we identified mammalian target of rapamycin complex 2 (mTORC2) as a central regulator of bladder cancer cell migration and invasion. mTORC2 ac...

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Detalhes bibliográficos
Main Authors: Gupta, Sounak, Hau, Andrew M., Beach, Jordan R., Harwalker, Jyoti, Mantuano, Elisabetta, Gonias, Steven L., Egelhoff, Thomas T., Hansel, Donna E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842329/
https://ncbi.nlm.nih.gov/pubmed/24312263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081081
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