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Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2)

mTOR (mammalian target of rapamycin) responds to the presence of nutrients, energy and growth factors to link cellular metabolism, growth and proliferation. The rapamycin-sensitive mTORC (mTOR complex) 1 activates the translational regulator S6K (S6 kinase), leading to increased protein synthesis in...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: DeStefano, Michael A., Jacinto, Estela
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881742/
https://ncbi.nlm.nih.gov/pubmed/23863152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130018
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