Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2)

The mechanistic target of rapamycin (mTOR) exists in two complexes that regulate diverse cellular processes. mTOR complex 1 (mTORC1), the canonical target of rapamycin, has been well studied, whereas the physiological role of mTORC2 remains relatively uncharacterized. In mice in which the mTORC2 com...

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Главные авторы: Lamming, Dudley W., Demirkan, Gokhan, Boylan, Joan M., Mihaylova, Maria M., Peng, Tao, Ferreira, Jonathan, Neretti, Nicola, Salomon, Arthur, Sabatini, David M., Gruppuso, Philip A.
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2014
Предметы:
Research Communications
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868844/
https://ncbi.nlm.nih.gov/pubmed/24072782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-237743
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