Transforming Growth Factor-β Is an Upstream Regulator of Mammalian Target of Rapamycin Complex 2–Dependent Bladder Cancer Cell Migration and Invasion

Our prior work identified the mammalian target of rapamycin complex 2 (mTORC2) as a key regulator of bladder cancer cell migration and invasion, although upstream growth factor mediators of this pathway in bladder cancer have not been well delineated. We tested whether transforming growth factor (TG...

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Publicado no:Am J Pathol
Main Authors: Gupta, Sounak, Hau, Andrew M., Al-Ahmadie, Hikmat A., Harwalkar, Jyoti, Shoskes, Aaron C., Elson, Paul, Beach, Jordan R., Hussey, George S., Schiemann, William P., Egelhoff, Thomas T., Howe, Philip H., Hansel, Donna E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861762/
https://ncbi.nlm.nih.gov/pubmed/26988652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.01.008
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https://ncbi.nlm.nih.gov/pmc/articles/PMC4861762/
https://ncbi.nlm.nih.gov/pubmed/26988652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.01.008