Mammalian Target of Rapamycin (mTOR) Regulates Cellular Proliferation and Tumor Growth in Urothelial Carcinoma

Mammalian target of rapamycin (mTOR) signaling has been associated with aggressive tumor growth in many cancer models, although its role in urothelial carcinoma (UCC) has not been extensively explored. Expression of phosphorylated mTOR (P-mTOR) and a downstream target, ribosomal S6 protein (P-S6), w...

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Bibliographische Detailangaben
Hauptverfasser: Hansel, Donna E., Platt, Eric, Orloff, Mohammed, Harwalker, Jyoti, Sethu, Swathi, Hicks, Jessica L., De Marzo, Angelo, Steinle, Roxanne E., Hsi, Eric D., Theodorescu, Dan, Ching, Christina B., Eng, Charis
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877865/
https://ncbi.nlm.nih.gov/pubmed/20395440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090872
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