Mammalian Target of Rapamycin (mTOR) Regulates Cellular Proliferation and Tumor Growth in Urothelial Carcinoma

Mammalian target of rapamycin (mTOR) signaling has been associated with aggressive tumor growth in many cancer models, although its role in urothelial carcinoma (UCC) has not been extensively explored. Expression of phosphorylated mTOR (P-mTOR) and a downstream target, ribosomal S6 protein (P-S6), w...

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Autors principals: Hansel, Donna E., Platt, Eric, Orloff, Mohammed, Harwalker, Jyoti, Sethu, Swathi, Hicks, Jessica L., De Marzo, Angelo, Steinle, Roxanne E., Hsi, Eric D., Theodorescu, Dan, Ching, Christina B., Eng, Charis
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877865/
https://ncbi.nlm.nih.gov/pubmed/20395440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090872
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