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The VDAC2-BAK Rheostat Controls Thymocyte Survival
The proapoptotic proteins BAX and BAK constitute the mitochondrial apoptotic gateway that executes cellular demise after integrating death signals. The lethal BAK is kept in check by voltage-dependent anion channel 2 (VDAC2), a mammalian-restricted VDAC isoform. Here, we provide evidence showing a c...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3842237/ https://ncbi.nlm.nih.gov/pubmed/19706873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000274 |
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