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The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage

Three forms of cell death have been described: apoptosis, autophagic cell death, and necrosis. Although genetic and biochemical studies have formulated a detailed blueprint concerning the apoptotic network, necrosis is generally perceived as a passive cellular demise resulted from unmanageable physi...

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Main Authors: Tu, Ho-Chou, Ren, Decheng, Wang, Gary X., Chen, David Y., Westergard, Todd D., Kim, Hyungjin, Sasagawa, Satoru, Hsieh, James J.-D., Cheng, Emily H.-Y.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633558/
https://ncbi.nlm.nih.gov/pubmed/19144918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808173106
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