The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons

PINK1 and PARKIN are causal genes for hereditary Parkinsonism. Recent studies have shown that PINK1 and Parkin play a pivotal role in the quality control of mitochondria, and dysfunction of either protein likely results in the accumulation of low-quality mitochondria that triggers early-onset famili...

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Bibliografski detalji
Glavni autori: Koyano, Fumika, Okatsu, Kei, Ishigaki, Shinsuke, Fujioka, Yusuke, Kimura, Mayumi, Sobue, Gen, Tanaka, Keiji, Matsuda, Noriyuki
Format: Artigo
Jezik:Inglês
Izdano: Wiley Publishing 2013
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842116/
https://ncbi.nlm.nih.gov/pubmed/23751051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gtc.12066
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