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Molecular interactions involved in proton-dependent gating in KcsA potassium channels
The bacterial potassium channel KcsA is gated open by the binding of protons to amino acids on the intracellular side of the channel. We have identified, via channel mutagenesis and x-ray crystallography, two pH-sensing amino acids and a set of nearby residues involved in molecular interactions that...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840921/ https://ncbi.nlm.nih.gov/pubmed/24218397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311057 |
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