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The voltage-dependent gate in MthK potassium channels is located at the selectivity filter

Understanding how ion channels open and close their pores is crucial for understanding their physiological roles. We used intracellular quaternary ammonium blockers to locate the voltage-dependent gate in MthK potassium channels from Methanobacterium thermoautotrophicum with electrophysiology and X-...

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Autori principali: Posson, David J., McCoy, Jason G., Nimigean, Crina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565016/
https://ncbi.nlm.nih.gov/pubmed/23262489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2473
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