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The voltage-dependent gate in MthK potassium channels is located at the selectivity filter

Understanding how ion channels open and close their pores is crucial for understanding their physiological roles. We used intracellular quaternary ammonium blockers to locate the voltage-dependent gate in MthK potassium channels from Methanobacterium thermoautotrophicum with electrophysiology and X-...

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Autors principals: Posson, David J., McCoy, Jason G., Nimigean, Crina M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3565016/
https://ncbi.nlm.nih.gov/pubmed/23262489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2473
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