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Calcium ions open a selectivity filter gate during activation of the MthK potassium channel

Ion channel opening and closing are fundamental to cellular signalling and homeostasis. Gates that control K(+) channel activity were found both at an intracellular pore constriction and within the selectivity filter near the extracellular side but the specific location of the gate that opens Ca(2+)...

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Publicat a:Nat Commun
Autors principals: Posson, David J., Rusinova, Radda, Andersen, Olaf S., Nimigean, Crina M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Pub. Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580985/
https://ncbi.nlm.nih.gov/pubmed/26395539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9342
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