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Mechanism for selectivity-inactivation coupling in KcsA potassium channels
Structures of the prokaryotic K(+) channel, KcsA, highlight the role of the selectivity filter carbonyls from the GYG signature sequence in determining a highly selective pore, but channels displaying this sequence vary widely in their cation selectivity. Furthermore, variable selectivity can be fou...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
National Academy of Sciences
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069191/ https://ncbi.nlm.nih.gov/pubmed/21402935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014186108 |
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