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Molecular mechanism of pH sensing in KcsA potassium channels

The bacterial potassium channel KcsA is gated by high concentrations of intracellular protons, allowing the channel to open at pH < 5.5. Despite prior attempts to determine the mechanism responsible for pH gating, the proton sensor has remained elusive. We have constructed a KcsA channel mutant t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Thompson, Ameer N., Posson, David J., Parsa, Pirooz V., Nimigean, Crina M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383984/
https://ncbi.nlm.nih.gov/pubmed/18443286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800873105
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