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Molecular mechanism of pH sensing in KcsA potassium channels
The bacterial potassium channel KcsA is gated by high concentrations of intracellular protons, allowing the channel to open at pH < 5.5. Despite prior attempts to determine the mechanism responsible for pH gating, the proton sensor has remained elusive. We have constructed a KcsA channel mutant t...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2383984/ https://ncbi.nlm.nih.gov/pubmed/18443286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800873105 |
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