Mechanism for selectivity-inactivation coupling in KcsA potassium channels

Structures of the prokaryotic K(+) channel, KcsA, highlight the role of the selectivity filter carbonyls from the GYG signature sequence in determining a highly selective pore, but channels displaying this sequence vary widely in their cation selectivity. Furthermore, variable selectivity can be fou...

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Detaylı Bibliyografya
Asıl Yazarlar: Cheng, Wayland W. L., McCoy, Jason G., Thompson, Ameer N., Nichols, Colin G., Nimigean, Crina M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069191/
https://ncbi.nlm.nih.gov/pubmed/21402935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014186108
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