CSF-1R inhibition alters macrophage polarization and blocks glioma progression

Glioblastoma multiforme (GBM) comprises several molecular subtypes including proneural GBM. Most therapeutic approaches targeting glioma cells have failed. An alternative strategy is to target cells in the glioma microenvironment, such as tumor-associated macrophages and microglia (TAMs). Macrophage...

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Detalhes bibliográficos
Main Authors: Pyonteck, Stephanie M., Akkari, Leila, Schuhmacher, Alberto J., Bowman, Robert L., Sevenich, Lisa, Quail, Daniela F., Olson, Oakley C., Quick, Marsha L., Huse, Jason T., Teijeiro, Virginia, Setty, Manu, Leslie, Christina S., Oei, Yoko, Pedraza, Alicia, Zhang, Jianan, Brennan, Cameron W., Sutton, James C., Holland, Eric C., Daniel, Dylan, Joyce, Johanna A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840724/
https://ncbi.nlm.nih.gov/pubmed/24056773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3337
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