Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer

Proteases are important for regulating multiple tumorigenic processes, including angiogenesis, tumor growth, and invasion. Elevated protease expression is associated with poor patient prognosis across numerous tumor types. Several multigene protease families have been implicated in cancer, including...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Akkari, Leila, Gocheva, Vasilena, Quick, Marsha L., Kester, Jemila C., Spencer, Alison K., Garfall, Alfred L., Bowman, Robert L., Joyce, Johanna A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719311/
https://ncbi.nlm.nih.gov/pubmed/26773004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.270439.115
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