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Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer

Proteases are important for regulating multiple tumorigenic processes, including angiogenesis, tumor growth, and invasion. Elevated protease expression is associated with poor patient prognosis across numerous tumor types. Several multigene protease families have been implicated in cancer, including...

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Bibliografiska uppgifter
I publikationen:Genes Dev
Huvudupphovsmän: Akkari, Leila, Gocheva, Vasilena, Quick, Marsha L., Kester, Jemila C., Spencer, Alison K., Garfall, Alfred L., Bowman, Robert L., Joyce, Johanna A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719311/
https://ncbi.nlm.nih.gov/pubmed/26773004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.270439.115
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