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Identification and preclinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model

Proteolytic activity is required for several key processes in cancer development and progression, including tumor growth, invasion and metastasis. Accordingly, high levels of protease expression and activity have been found to correlate with malignant progression and poor patient prognosis in a wide...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Elie, Benelita Tina, Gocheva, Vasilena, Shree, Tanaya, Dalrymple, Stacie A., Holsinger, Leslie J., Joyce, Johanna A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814225/
https://ncbi.nlm.nih.gov/pubmed/20447439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2010.04.023
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