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Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

Multiple types of degradative enzymes, including cathepsins of the cysteine protease family, have been implicated in the regulation of angiogenesis and invasion during cancer progression. Several cysteine cathepsins are up-regulated in a mouse model of pancreatic islet cell carcinogenesis (RIP1-Tag2...

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Bibliographic Details
Main Authors: Gocheva, Vasilena, Zeng, Wei, Ke, Danxia, Klimstra, David, Reinheckel, Thomas, Peters, Christoph, Hanahan, Douglas, Joyce, Johanna A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1410800/
https://ncbi.nlm.nih.gov/pubmed/16481467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1407406
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