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Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer

Proteases can regulate many aspects of tumor development as their actions, which include degradation of the extracellular matrix, proteolytic processing of chemokines and activation of other enzymes, influence a number of key tumorigenic processes. Members of one protease class, the cysteine catheps...

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Bibliografiske detaljer
Main Authors: Gocheva, Vasilena, Chen, Xiaoping, Peters, Christoph, Reinheckel, Thomas, Joyce, Johanna A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126667/
https://ncbi.nlm.nih.gov/pubmed/20731543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2010.080
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