Macrophage ontogeny underlies differences in tumor-specific education in brain malignancies

Extensive transcriptional and ontogenetic diversity exists among normal tissue-resident macrophages, with unique transcriptional profiles endowing the cells with tissue-specific functions. However, it is unknown whether the origins of different macrophage populations affect their roles in malignancy...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Bowman, Robert L., Klemm, Florian, Akkari, Leila, Pyonteck, Stephanie M., Sevenich, Lisa, Quail, Daniela F., Dhara, Surajit, Simpson, Kenishana, Gardner, Eric E., Iacobuzio-Donahue, Christine A., Brennan, Cameron W., Tabar, Viviane, Gutin, Philip H., Joyce, Johanna A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450644/
https://ncbi.nlm.nih.gov/pubmed/27840052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.052
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