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An n→π* Interaction Reduces the Electrophilicity of the Acceptor Carbonyl Group

Carbonyl–carbonyl (C=O···C′=O′) interactions are ubiquitous in both small and large molecular systems. This interaction involves delocalization of a lone pair (n) of a donor oxygen into the antibonding orbital (π*) of an acceptor carbonyl group. Analyses of high-resolution protein structures suggest...

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Detalhes bibliográficos
Main Authors: Choudhary, Amit, Fry, Charles G., Kamer, Kimberli J., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840071/
https://ncbi.nlm.nih.gov/pubmed/23928794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc44573a
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