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Visualization of local DNA unwinding by Mre11/Rad50/Nbs1 using single-molecule FRET
The Mre11/Rad50/Nbs1 (MRN) complex initiates and coordinates DNA repair and signaling events at double-strand breaks. The interaction between MRN and DNA ends is critical for the recruitment of DNA-processing enzymes, end tethering, and activation of the ATM protein kinase. Here we visualized MRN bi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839711/ https://ncbi.nlm.nih.gov/pubmed/24191051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309816110 |
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