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HDAC Inhibition by LBH589 Affects Phenotype and Function of Human Myeloid Dendritic Cells
LBH589 is a novel pan-HDAC inhibitor which has potent antitumor activity in multiple myeloma and other hematologic malignancies. However, its impact on immune system has not been defined. We here evaluated the effects of LBH589 on human myeloid dendritic cells (DCs) at clinically relevant concentrat...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839585/ https://ncbi.nlm.nih.gov/pubmed/21102427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.244 |
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