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HDAC Inhibitor LBH589 Suppresses the Proliferation but Enhances the Antileukemic Effect of Human γδT Cells

γδT cells have potent effects on hematological malignancies, and their functions can be regulated by anti-tumor agents. Histone deacetylase inhibitors (HDACis) not only have antileukemic activity on leukemia but also affect immune cells during therapeutic application. In this in vitro study, we show...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: He, Ying, Xu, Lin, Feng, Jingjing, Wu, Kangni, Zhao, Yanmin, Huang, He
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515977/
https://ncbi.nlm.nih.gov/pubmed/33005729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.08.003
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