Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat)

Aromatase inhibitors (AIs) are important drugs for treating postmenopausal patients with hormone receptor (HR)-positive breast cancer. However, acquired resistance to AI therapies is a significant problem. Our study has revealed that the histone deacetylase inhibitor LBH589 treatment abrogated growt...

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Hlavní autoři: Kubo, Makoto, Kanaya, Noriko, Petrossian, Karineh, Ye, Jingjing, Warden, Charles, Liu, Zheng, Nishimura, Reiki, Osako, Tomofumi, Okido, Masayuki, Shimada, Kazuo, Takahashi, Masato, Chu, Peiguo, Yuan, Yate-Ching, Chen, Shiuan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637924/
https://ncbi.nlm.nih.gov/pubmed/23160924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2332-x
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