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1, 1-Bis (3′-indolyl)-1-(p-substituted phenyl) methane compounds inhibit lung cancer cell and tumor growth in a metastasis model

1,1-Bis(3-indolyl)-1-(p-substitutedphenyl)methane (C-DIM) compounds exhibit remarkable antitumor activity with low toxicity in various cancer cells including lung tumors. Two C-DIM analogs, DIM-C-pPhOCH3 (C-DIM-5) and DIM-C-pPhOH (C-DIM-8) while acting differentially on the orphan nuclear receptor,...

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Autors principals: Andey, Terrick, Patel, Apurva, Jackson, Tanise, Safe, Stephen, Singh, Mandip
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838903/
https://ncbi.nlm.nih.gov/pubmed/23892137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2013.07.007
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