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1,1-Bis(3′-Indolyl)-1-(p-Substituted Phenyl)Methanes Decrease Mitochondrial Membrane Potential and Induce Apoptosis in Endometrial and Other Cancer Cell Lines

1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes, containing p-t-butyl (DIM-C-pPhtBu) and phenyl (DIM-C-pPhC(6)H(5)) substituents, are peroxisome proliferator-activated receptor γ (PPARγ) agonists; however, DIM-C-pPhtBu-induced growth inhibition and cell death in human HEC1A endometrial cancer c...

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Detalhes bibliográficos
Main Authors: Hong, Jun, Samudio, Ismael, Chintharlapalli, Sudhakar, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711558/
https://ncbi.nlm.nih.gov/pubmed/18085536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20407
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