Загрузка...

1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase

1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes (C-DIMs) activate the orphan receptors peroxisome proliferator-activated receptor γ (PPARγ) and Nur77 and induce receptor-dependent and -independent apoptotic pathways in colon and other cancer cells. Structure-activity studies show that the p-bro...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Lei, Ping, Abdelrahim, Maen, Cho, Sung Dae, Liu, Shengxi, Chintharlapalli, Sudhakar, Safe, Stephen
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574736/
https://ncbi.nlm.nih.gov/pubmed/18460448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn103
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!