5,5′-Dibromo-bis(3′-indolyl)methane induces Krüppel-like factor 4 and p21 in colon cancer cells

Bis(3′-indolyl)methane (DIM) is a metabolite of the phytochemical indole-3-carbinol, and both compounds exhibit a broad spectrum of anticancer activities. We have developed a series of synthetic symmetrical ring-substituted DIM analogues, including 5,5′-dibromoDIM, which are more potent than DIM as...

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Hlavní autoři: Dae Cho, Sung, Chintharlapalli, Sudhakar, Abdelrahim, Maen, Papineni, Sabitha, Liu, Shengxi, Guo, Jingjing, Lei, Ping, Abudayyeh, Ala, Safe, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2565496/
https://ncbi.nlm.nih.gov/pubmed/18645021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2311
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