Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model

The role of side populations (SP) or cancer stem-like cells (CSC) in promoting the resistance phenotype presents a viable anticancer target. Human-derived H1650 SP cells over-express annexin A2 (AnxA2) and SOX2, and are resistant to conventional cytotoxic chemotherapeutics. AnxA2 and SOX2 bind to pr...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Andey, Terrick, Marepally, Srujan, Patel, Apurva, Jackson, Tanise, Sarkar, Shubhashish, O’Connell, Malaney, Reddy, Rakesh C, Chellappan, Srikumar, Singh, Pomila, Singh, Mandip
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674431/
https://ncbi.nlm.nih.gov/pubmed/24727000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.03.049
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