Epigenetic regulation of human DCLK-1 gene during colon-carcinogenesis: clinical and mechanistic implications

Por Singh, Pomila, O’Connell, Malaney, Shubhashish, Sarkar
Publicado no Stem Cell Investig (2016)

Curcumin Promotes Autophagic Survival of a Sub-Set of Colon Cancer Stem Cells, which are Ablated by DCLK1-siRNA

Por Kantara, Carla, O’Connell, Malaney, Sarkar, Shubhashish, Moya, Stephanie, Ullrich, Robert, Singh, Pomila
Publicado em 2014

Methods for Detecting Circulating Cancer Stem Cells (CCSCs) as a Novel Approach for Diagnosis of Colon Cancer Relapse/Metastasis

Por Kantara, Carla, O’Connell, Malaney, Luthra, Gurinder, Gajjar, Aakash, Sarkar, Shubhashish, Ullrich, Robert, Singh, Pomila
Publicado no Lab Invest (2014)

FOXD3 Regulates CSC Marker, DCLK1-S, and Invasive Potential: Prognostic Implications in Colon Cancer

Por Sarkar, Shubhashish, O’Connell, Malaney R., Okugawa, Yoshinaga, Lee, Brian S., Toiyama, Yuji, Kusunoki, Masato, Daboval, Robert D., Goel, Ajay, Singh, Pomila
Publicado no Mol Cancer Res (2017)

Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications

Por O’Connell, Malaney R., Sarkar, Shubhashish, Luthra, Gurinder K., Okugawa, Yoshinaga, Toiyama, Yuji, Gajjar, Aakash H., Qiu, Suimin, Goel, Ajay, Singh, Pomila
Publicado no Sci Rep (2015)

Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model

Por Andey, Terrick, Marepally, Srujan, Patel, Apurva, Jackson, Tanise, Sarkar, Shubhashish, O’Connell, Malaney, Reddy, Rakesh C, Chellappan, Srikumar, Singh, Pomila, Singh, Mandip
Publicado no J Control Release (2014)

CD90(+) stromal cells are the major source of IL-6 which supports cancer stem-like cells and inflammation in colorectal cancer

Por Huynh, Phuong T., Beswick, Ellen J., Coronado, Yun A., Johnson, Paul, O'Connell, Malaney R., Watts, Tammara, Singh, Pomila, Qiu, Suimin, Morris, Katherine, Powell, Don W., Pinchuk, Irina V.
Publicado no Int J Cancer (2015)