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Curcumin Promotes Autophagic Survival of a Sub-Set of Colon Cancer Stem Cells, which are Ablated by DCLK1-siRNA

Curcumin is known to induce apoptosis of cancer cells by different mechanisms, but its effects on cancer stem-like cells have been less investigated. Here we report that curcumin promotes the survival of DCLK1-positive colon cancer stem-like cells (CSC), potentially confounding application of its an...

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Detaylı Bibliyografya
Asıl Yazarlar: Kantara, Carla, O’Connell, Malaney, Sarkar, Shubhashish, Moya, Stephanie, Ullrich, Robert, Singh, Pomila
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013529/
https://ncbi.nlm.nih.gov/pubmed/24626093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3536
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