Formulation, Pharmacokinetic, and Efficacy Studies of Mannosylated Self-Emulsifying Solid Dispersions of Noscapine

PURPOSE: To formulate hydroxypropyl methylcellulose-stabilized self-emulsifying solid dispersible carriers of noscapine to enhance oral bioavailability. METHODS: Formulation of noscapine (Nos) self-emulsifying solid dispersible microparticles (SESDs) was afforded by emulsification using an optimized...

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Bibliographic Details
Published in:PLoS One
Main Authors: Andey, Terrick, Patel, Apurva, Marepally, Srujan, Chougule, Mahavir, Spencer, Shawn D., Rishi, Arun K., Singh, Mandip
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710382/
https://ncbi.nlm.nih.gov/pubmed/26757437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146804
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