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Enhanced Anticancer Activity of Gemcitabine in Combination with Noscapine via Antiangiogenic and Apoptotic Pathway against Non-Small Cell Lung Cancer

BACKGROUND: The aim of this investigation was to evaluate the anticancer activity of Noscapine (Nos) and Gemcitabine (Gem) combination (NGC) against non-small cell lung cancer (NSCLC) and to elucidate the underlying mechanism of action. METHODS: Isobolographic method was used to calculate combinatio...

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Autors principals: Chougule, Mahavir B., Patel, Apurva, Sachdeva, Pratik, Jackson, Tanise, Singh, Mandip
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216931/
https://ncbi.nlm.nih.gov/pubmed/22102891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027394
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