Chemoprevention of Skin Cancer with 1,1-Bis (3′-Indolyl)-1-(Aromatic) Methane Analog through Induction of the Orphan Nuclear Receptor, NR4A2 (Nurr1)

BACKGROUND: The objective of this study was to demonstrate the anti-skin cancer and chemopreventive potential of 1,1-bis(3′-indolyl)-1-(p-chlorophenyl methane) (DIM-D) using an in vitro model. METHODS: In vitro cell cytotoxicity and viability assays were carried out in A431 human epidermoid carcinom...

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Detalhes bibliográficos
Main Authors: Boakye, Cedar H. A., Doddapaneni, Ravi, Shah, Punit P., Patel, Apurva R., Godugu, Chandraiah, Safe, Stephen, Katiyar, Santosh K., Singh, Mandip
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737220/
https://ncbi.nlm.nih.gov/pubmed/23950896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069519
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