Chronic inhibition of cGMP-specific phosphodiesterase 5 suppresses endoplasmic reticulum stress in heart failure

BACKGROUND AND PURPOSE: Inhibition of the cGMP-specific phosphodiesterase 5 (PDE5) exerts profound beneficial effects on failing hearts. However, the mechanisms underlying the therapeutic effects of PDE5 inhibition on heart failure are unclear. The purpose of this study was to investigate whether PD...

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Bibliografiska uppgifter
Huvudupphovsmän: Gong, Wei, Duan, Quanlu, Cai, Zhejun, Chen, Chen, Ni, Li, Yan, Mengwen, Wang, Xingxu, Cianflone, Katherine, Wang, Dao Wen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2013
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838686/
https://ncbi.nlm.nih.gov/pubmed/24032459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12346
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