CYP2J2-Derived Epoxyeicosatrienoic Acids Suppress Endoplasmic Reticulum Stress in Heart Failure

Prolonged endoplasmic reticulum (ER) stress causes apoptosis and is associated with heart failure. Whether CYP2J2 and its arachidonic acid metabolites [epoxyeicosatrienoic acids (EETs)] have a protective influence on ER stress and heart failure has not been studied. Assays of myocardial samples from...

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Bibliografiske detaljer
Main Authors: Wang, Xingxu, Ni, Li, Yang, Lei, Duan, Quanlu, Chen, Chen, Edin, Matthew L., Zeldin, Darryl C., Wang, Dao Wen
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2014
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868901/
https://ncbi.nlm.nih.gov/pubmed/24145329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.087122
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