CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages

Cytochrome P450 epoxygenase (CYP450)-derived epoxyeicosatrienoic acids (EETs) are important regulators of cardiac remodeling; but the underlying mechanism remains unclear. The present study aimed to elucidate how EETs regulated cardiac fibrosis in response to isoprenaline (Iso) or angiotensin (Ang)...

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Detalhes bibliográficos
Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Yang, Lei, Ni, Li, Duan, Quanlu, Wang, Xingxu, Chen, Chen, Chen, Song, Chaugai, Sandip, Zeldin, D.C., Tang, Jia Rong, Wang, Dao Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533100/
https://ncbi.nlm.nih.gov/pubmed/25686540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2015.01.004
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