Intestinal GUCY2C Prevents TGF-β Secretion Coordinating Desmoplasia and Hyperproliferation in Colorectal Cancer

Tumorigenesis is a multi-step process that reflects intimate reciprocal interactions between epithelia and underlying stroma. However, tumor-initiating mechanisms coordinating transformation of both epithelial and stromal components are not defined. In humans and mice, initiation of colorectal cance...

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Hlavní autoři: Gibbons, Ahmara V., Lin, Jieru E., Kim, Gilbert W., Marszalowicz, Glen P., Li, Peng, Stoecker, Brian A., Blomain, Erik S., Rattan, Satish, Snook, Adam E., Schulz, Stephanie, Waldman, Scott A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838632/
https://ncbi.nlm.nih.gov/pubmed/24085786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0887
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