A carregar...
Hepatic Basolateral Efflux Contributes Significantly to Rosuvastatin Disposition I: Characterization of Basolateral Versus Biliary Clearance Using a Novel Protocol in Sandwich-Cultured Hepatocytes
Transporters responsible for hepatic uptake and biliary clearance (CL(Bile)) of rosuvastatin (RSV) have been well characterized. However, the contribution of basolateral efflux clearance (CL(BL)) to hepatic and systemic exposure of RSV is unknown. Additionally, the appropriate design of in vitro hep...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3836307/ https://ncbi.nlm.nih.gov/pubmed/24023367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.207472 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|