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Simultaneous knock-down of Bcl-xL and Mcl-1 induces apoptosis through Bax activation in pancreatic cancer cells
Anti-apoptotic Bcl-2 family proteins have been reported to play an important role in apoptotic cell death of human malignancies. The aim of this study was to delineate the mechanism of anti-apoptotic Bcl-2 family proteins in pancreatic cancer (PaCa) cell survival. We first analyzed the endogenous ex...
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Autores principales: | , , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834082/ https://ncbi.nlm.nih.gov/pubmed/23954445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2013.08.006 |
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