BAICALEIN, A COMPONENT OF SCUTELLARIA BAICALENSIS, INDUCES APOPTOSIS BY MCL-1 DOWN-REGULATION IN HUMAN PANCREATIC CANCER CELLS

Scutellaria baicalensis (SB) and SB-derived polyphenols possess anti-proliferative activities in several cancers, including pancreatic cancer (PaCa). However, the precise molecular mechanisms have not been fully defined. SB extract and SB-derived polyphenols (wogonin, baicalin, and baicalein) were u...

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Main Authors: Takahashi, Hiroki, Chen, Monica C., Pham, Hung, Angst, Eliane, King, Jonathan C., Park, Jenny, Brovman, Ethan Y., Ishiguro, Hideyuki, Harris, Diane M., Reber, Howard A., Hines, Oscar J., Gukovskaya, Anna S., Go, Vay Liang W., Eibl, Guido
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123440/
https://ncbi.nlm.nih.gov/pubmed/21596068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.05.003
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