The live attenuated chimeric vaccine rWN/DEN4Δ30 is well-tolerated and immunogenic in healthy flavivirus-naïve adult volunteers

WNV has become the leading vector-borne cause of meningoencephalitis in the United States. Although the majority of WNV infections result in asymptomatic illness, approximately 20% of infections result in West Nile fever and 1% in West Nile neuroinvasive disease (WNND), which causes encephalitis, me...

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Autors principals: Durbin, Anna P., Wright, Peter F., Cox, Amber, Kagucia, Wangeci, Elwood, Daniel, Henderson, Susan, Wanionek, Kimberli, Speicher, Jim, Whitehead, Stephen S., Pletnev, Alexander G.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833717/
https://ncbi.nlm.nih.gov/pubmed/23968769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.07.064
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