A Single Dose of the DENV-1 Candidate Vaccine rDEN1Δ30 Is Strongly Immunogenic and Induces Resistance to a Second Dose in a Randomized Trial

Dengue is an emerging infectious disease that has become the most important arboviral infection worldwide. There are four serotypes of dengue virus, DENV-1, DENV-2, DENV-3, and DENV-4, each capable of causing the full spectrum of disease. rDEN1Δ30 is a live attenuated investigational vaccine for the...

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Detalhes bibliográficos
Main Authors: Durbin, Anna P., Whitehead, Stephen S., Shaffer, Donna, Elwood, Dan, Wanionek, Kimberli, Thumar, Bhavin, Blaney, Joseph E., Murphy, Brian R., Schmidt, Alexander C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149013/
https://ncbi.nlm.nih.gov/pubmed/21829748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001267
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