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Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4

Langat virus (LGT) strain TP21 is the most attenuated of the tick-borne flaviviruses for humans. Even though LGT has low-level neurovirulence for humans, it, and its more attenuated egg-passage derivative, strain E5, exhibit significant neurovirulence and neuroinvasiveness in normal mice, albeit les...

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Bibliografski detalji
Glavni autori: Pletnev, Alexander G., Men, Ruhe
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC19176/
https://ncbi.nlm.nih.gov/pubmed/9465088
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