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Chimeric Tick-Borne Encephalitis/Dengue Virus Is Attenuated in Ixodes scapularis Ticks and Aedes aegypti Mosquitoes
In an effort to derive an efficacious live attenuated vaccine against tick-borne encephalitis, we generated a chimeric virus bearing the structural protein genes of a Far Eastern subtype of tick-borne encephalitis virus (TBEV) on the genetic background of recombinant dengue 4 (DEN4) virus. Introduct...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Mary Ann Liebert, Inc.
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115420/ https://ncbi.nlm.nih.gov/pubmed/21142950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vbz.2010.0179 |
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