Orphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in rats

OBJECTIVE: Intracerebroventricular administration of orphanin FQ/nociceptin (OFQ/N), the endogenous agonist ligand of the opioid receptor-like (ORL-1) receptor, decreases extracellular levels of dopamine and suppresses motor activity. The presence of the ORL-1 receptor on mesoaccumbal and nigrostria...

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Detalles Bibliográficos
Publicado en:J Psychiatry Neurosci
Main Authors: Narayanan, Shridhar, Lam, Hoa, Carroll, F. Ivy, Lutfy, Kabirullah
Formato: Artigo
Idioma:Inglês
Publicado: Canadian Science Publishing 2004
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15069465/
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